If a cancer responds to the chemotherapy, meaning it shrinks or vanishes after a person receives the chemo drugs, the cancer is described as "chemosensitive." The opposite of progressive disease is stable disease or static disease: a medical condition that exists, but does not get better or worse. Refractory MG is not completely understood. Despite the overall decreasing mortality in paediatric patients with sepsis in recent years, refractory septic shock (RSS) that is unresponsive to standard resuscitation is still associated with very poor outcomes. • REFRACTORY (adjective) The adjective REFRACTORY has 3 senses:. It is 2007-12-07ot;difficult” symptoms, since many symptoms considered refractory are at times successfully managed by specialized hospice and palliative care programs (Broeckaert 2002).The malignant tumors most often associated with refractory symptoms include those in the lungs, gastrointestinal tract, head and neck, … The definition of refractory gastroesophageal reflux disease (GERD) is controversial [ 1 ]. 1. Refractory metals are the metallic elements with the highest melting point, high … Excitability is defined as the capacity of cells to generate an action potential in response to inward - Osmosis is an efficient, enjoyable, and social way to learn. Manage the airway, if necessary. A feeling of fullness after eating just a few bites. Refractory cancer refers to cancer that may be resistant at the beginning of treatment, or becomes resistant during treatment. Learn more. Definition and Etiology. 2. MedicineNet does not provide medical advice, diagnosis or treatment. b : unresponsive to stimulus. c : immune, insusceptible after recovery they were refractory to infection. Refractories are polycrystalline, polyphase, inorganic, non-metallic, porous, and heterogeneous. Refractory celiac disease (RCD) is a complex autoimmune disorder much like the more common celiac disease but, unlike celiac disease, it is resistant or unresponsive to at least 12 months of treatment with a strict gluten-free diet. Paroxysmal & Refractory Atrial Fibrillation. refractory answers are found in the Taber's Medical Dictionary powered by Unbound Medicine. About one-third of people with epilepsy will eventually develop refractory epilepsy. Medical professionals have used physiological changes to the body as a basis for a definition, whereas psychologists and mental health professionals have … 1. a refractory illness does not improve despite medical treatment. Many people with … A condition or tendency, … If a cancer responds to the chemotherapy, meaning it shrinks or vanishes after a person receives the chemo drugs, the cancer is described as "chemosensitive." [ re-frak´tah-re] 1. not readily yielding to treatment. Subclinical disease Terence Bell. Refractory disease A refractory disease is a disease that resists treatment, especially an individual case that resists treatment more than is normal for the specific disease in question. January 31, 2018. The word “refractory” in general use means stubborn or intractable, and in medicine it is specifically applied to disease that does not respond to treatment. : the period immediately following the firing of a nerve fiber when it cannot be stimulated no matter how great a stimulus is applied. Medical Definition of absolute refractory period. Terms of Use. 2. a refractory [= disobedient] child. Tools. 2. formal : difficult to control or deal with. Refractory definition, hard or impossible to manage; stubbornly disobedient: a refractory child. These syndromes are characterized by ineffective hematopoiesis manifested in morphologic dysplasia of hematopoietic precursors, one or more peripheral blood cytopenias, and a propensity to progress to … Synonyms for refractory in Free Thesaurus. In some cases, refractory migraine is used synonymously with chronic migraine, or referred to as intractable migraine. Medical Definition of relative refractory period : the period shortly after the firing of a nerve fiber when partial repolarization has occurred and a greater than normal stimulus can stimulate a second response — compare absolute refractory period Learn More About … Then, intractable, the one works best is highlighted in yellow – difficult to alleviate, remedy or … refractory ulcer synonyms, refractory ulcer pronunciation, refractory ulcer translation, English dictionary definition of refractory ulcer. Refractory epilepsy: a type of epilepsy that cannot be controlled by medications. Abdominal pain. The word “refractory” in general use means stubborn or intractable, and in medicine it is specifically applied to disease that does not respond to treatment. (n) information which includes increased melting point. 1. “Refractory metals” is one of those colloquial terms used to group materials with extremely high melting points. [more refractory; most refractory] 1. medical : difficult to treat or cure. Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. EPILEPSY, med. Legal Dictionary. The term refractory shock is applied when, in spite of apparently adequate therapy, the shock state continues. Define refractory period. Refractory status epilepticus (SE) is defined as a continuous seizures or a flurry of very frequent seizures that do not respond to standard anticonvulsant medications. 2. not responding to a stimulus. 2. not responding to a stimulus. RI - Refractory Index. SE describes a state in which a person has one prolonged seizure, or a cluster of … Refractory ventricular tachycardia, also known as “electrical storm,” is defined as at least two or more separate ventricular tachycardia (VT) or fibrillation (VF) episodes requiring intervention in a 24-hour period (1, 2, 3). Signs and symptoms of anaphylaxis include dizziness, trouble breathing, and swelling of your lips, eyelids and tongue. or a serious medical illness. Don't study it, Osmose it. Related to refractory anemia: Myelodysplastic syndrome , Refractory Anemia with Excess Blasts Category filter: Show All (189) Most Common (1) Technology (25) Government & Military (52) Science & Medicine (34) Business (30) Organizations (40) Slang / Jargon (24) 267-426-0762. Past medical records must be available to document chronicity, and the refractory nature of the disease. The term 'refractory metal' is used to describe a group of metal elements that have exceptionally high melting points and are resistant to wear, corrosion, and deformation. Changes in blood sugar levels. Available for iPhone, iPad, Android, and Web. Learn more. ... Medical Dictionary. Several terms have been used to describe this condition, including the recently introduced term cough hypersensitivity syndrome. An abnormal condition of a part, organ, or system of an organism resulting from various causes, such as infection, inflammation, environmental factors, or genetic defect, and characterized by an identifiable group of signs, symptoms, or both. The section of territory occupied by one of the United States. MDS is caused by various abnormalities of the bone marrow. -. n a period during which a nerve or muscle is incapable of responding to stimulation, esp immediately following a previous stimulation. One seemingly effective way to treat those who suffer from Refractory Hypoxemia is Neuromuscular Blockade (NMB). Refractory intracranial hypertension (ICH) is defined by recurrent episodes of intracranial pressure elevation above 20 mmHg for sustained periods (10–15 min) despite medical therapy. Definition 1: Palliative sedation is the intentional administration of sedative drugs in dosages and combinations required to reduce the consciousness of a terminal patient as much as necessary to adequately relieve one or more refractory symptoms. NCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine. Refractory Depression – Treatment, Definition, Severe March 24th, 2012 admin Types of Depression 0 comments Depression in itself is a complicated disorder, but there may be further complications that can make treating the condition a lot more challenging. It may also occur in people with a chronic seizure disorder. ABCs; Start with the basics. The definition of refractory gastroesophageal reflux disease (GERD) is controversial [ 1 ]. Websters Dictionary 1828 – Online Edition is an excellent reference for classical literature, Bible studies, history papers, and the reading of America's national documents. GERD in these patients is termed refractory GERD. Refractory metals share several features with each other, depending on the user’s definition. See more. Financial Dictionary. The test involves looking through a device called a phoropter to read letters or recognize symbols on a wall chart through lenses of … The refractory period is the time between orgasm and when you feel ready to be sexually aroused again. Thus, it is important to define the patient population that would now be considered as refractory to ruxolitinib vs ruxolitinib dependent. Refractory Epilepsy. n. Any of a group of disorders characterized by the abnormal proliferation of bone marrow cells that are precursors to blood cells. Lack of appetite. The word “refractory” in general use means stubborn or intractable, and in medicine it is specifically applied to disease that does not respond to treatment. Refractory cancer refers to cancer that may be resistant at the beginning of treatment, or becomes resistant during treatment. The usual electrical activity in the brain becomes altered. It is seen in 20-46% of patients presenting to specialist cough clinics and it has a substantial impact on quality of life and healthcare utilization. Referral of patients with refractory end-stage heart failure to a program with expertise in the management of refractory heart failure is useful. Refractory anemia may occur after a cancer patient undergoes chemotherapy treatment. Wikipedia Encyclopedia. The American Heritage® Medical Dictionary Copyright © … 215-590-3025. People with epilepsy have seizures. Refractory Period, Electrophysiological. The period of time following the triggering of an ACTION POTENTIAL when the CELL MEMBRANE has changed to an unexcitable state and is gradually restored to the resting (excitable) state. During the absolute refractory period no other stimulus can trigger a response. These paroxysms are characterized by the loss of sensation, and co These seizures may last a few seconds or a few minutes. In the medical literature, there are only a few references on refractory fibromyalgia and there is no consensus definition available on this concept. The refraction test, also termed vision test, is an examination that tests an individual’s ability to see an object at a specific distance. refractory ITP [1] as this is an appropriate interval to provide confidence that alternative etiologies of thrombocytopenia have been excluded and spontaneous remissions are unlikely. 4. Myelodysplastic syndrome, or MDS, is a type of cancer in which the bone marrow does not produce healthy cells. Refractory in AZ Dictionary. Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. Definition of Refractory epilepsy. Definition of refractory investment in the Financial Dictionary - by Free online English dictionary and encyclopedia. refractory. refractory. Refractory: Not yielding, or not yielding readily, to treatment. Myelodysplastic syndrome with multilineage dysplasia (MDS-MLD) is one of the more common myelodysplastic syndromes (MDS). The meaning of refractory cancer is cancer that fails to respond to medical treatment. B." Referral for cardiac transplantation in potentially eligible patients. a refractory disease. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved. This review will Chronic refractory cough (CRC) is defined as a cough that persists despite guideline based treatment. If you do experience hives as part of a serious allergic reaction, seek emergency care. 2 a : resistant to treatment or cure a refractory lesion. There is also no single definition. Sign up for an account today! According to most experts, patients with GERD who exhibit partial or lack of response to proton pump inhibitor (PPI) twice daily are considered to have failed PPI therapy [ 2 ]. This may present as resistance to treatment from the start, or … refractory meaning: 1. not affected by a treatment, change, or process: 2. difficult to control; unwilling to obey…. Ruxolitinib was recently approved for the treatment of corticosteroid-refractory acute GVHD in adult and pediatric patients 12 years and older. GERD can be subdivided into erosive reflux disease or nonerosive reflux disease (NERD) based on endoscopic findings. 1. not readily yielding to treatment. Showing or characterized by obstinate resistance to authority or control: refractory children; refractory behavior. Medical Definition of Leukemia, refractory Medical Author: William C. Shiel Jr., MD, FACP, FACR Leukemia, refractory: Leukemia in which the high level of white blood cells does not decrease in response to treatment. © 2003 by … Also found in: Dictionary, Thesaurus, Medical, Wikipedia. What does refractory investment mean in finance? Antonyms for refractory. Meticulous identification and control of fluid retention. This means that the affected person continues to have seizures even when taking anti-seziure medications. Definition of refractory gout • Symptomatic gout in which conventional urate-lowering therapies are contraindicated or the maximum medically appropriate dosage of these therapies does not control hyperuricemia • Recurrent and disabling gout flares • Chronic gout arthropathy with or without bony erosions • Visible progressive tophi The loss of a state of wellness due to a either a failure in physiologic adaptation mechanisms or an overwhelming of the natural defenses by a noxious agent or pathogen. — compare relative refractory period. While these episodes may be apparent to the patient, many are not recognized and may be totally asymptomatic. (a) Resistant to therapy: a refractory situation of acne. Refractory Neuroblastoma Program. It’s also called the “resolution” stage. Intractable pain can develop from several types of health problems. GERD in these patients is termed refractory GERD. Refractory Index listed as RI. A disease of the brain, which occurs in paroxysms, with uncertain intervals between them. It is Refractory Index. Encyclopedia. See additional information. Assemble your team. This article focuses on recognizing refractory GERD and refractory symptoms of GERD, the differential diagnosis, and the role of diagnostic testing and therapeutic options. Definition of Refractory Refractory: Not yielding, or not yielding readily, to treatment. Acid reflux. [+] more examples [-] hide examples [+] Example sentences [-] Hide examples. Other recent reviews have addressed the pathogenesis and diagnosis of ITP as well as management [5–9]. [ re-frak´tah-re] 1. not readily yielding to treatment. Anemia, refractory, Refractory anemia: Drug Medical Dictionary [home, info] Quick definitions from WordNet (refractory anemia) noun: any of various anemic conditions that are not successfully treated by any means other than blood transfusions (and that are not associated with another primary disease) 1. lining consisting of material with a high melting point; used to line the inside walls of a furnace Familiarity information: REFRACTORY used as a noun is very rare. It is the most common coagulation disorder among intensive care patients and is seen in 20% of medical patients and a third of surgical patients.. A normal human platelet count ranges from 150,000 to 450,000 platelets per microliter of blood. (n) One that is refractory. relative refractory period answers are found in the Taber's Medical Dictionary powered by Unbound Medicine. Abdominal bloating. Updated December 10, 2018. According to most experts, patients with GERD who exhibit partial or lack of response to proton pump inhibitor (PPI) twice daily are considered to have failed PPI therapy [ 2 ]. CONTINUE SCROLLING OR CLICK HERE. This means that the affected person continues to have seizures even when taking anti-seziure medications. Medical Definition of refractoriness : the insensitivity to further immediate stimulation that develops in irritable and especially nervous tissue as a result of intense or prolonged stimulation Learn More About refractoriness Dictionary Entries Near refractoriness 1916 - Appleton's medical dictionary Sort: Oldest first stubbornly resistant to authority or control ; " a fractious animal that would not submit to the harness "; " a refractory child " Definition of refractory. Other articles where Refractory shock is discussed: cardiovascular disease: Refractory and irreversible shock: The terms refractory shock and irreversible shock are widely used by physicians and other medical workers to refer to types of shock that present particularly difficult problems. However, most experts agree that having one or more of the following may be refractory MG: 1-3 MG symptoms that do not improve with typical drugs (including steroids, acetylcholinesterase [AChE] inhibitors, or at least 1 immune system-suppressing drug); Relapses that occur when trying to wean off of treatment Although women can (and do) develop refractory angina, it is a male dominated disease which generally affects men over the under the age of 70 years. For example: If the diagnosis is corrected and seizures can be brought under control with a different treatment, then they would not be considered refractory. (a) Obstinately resistant to expert or control. Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh … Documentation of the failure to resolve the following: surgical bony debridement and appropriate course of antibiotics. A number of different terms may be used to describe this type of epilepsy, including uncontrolled, intractable, refractory, or drug resistant. Some definitions of refractory fibromyalgia have been proposed based on the lack of response to a number of medications, and perhaps the most appropriate term is treatment-refractory fibromyalgia. 2. not responding to a stimulus. Refractory and Intractable – The refractory is, when you’re reading the definitions, the one that is the best from medical terms is – resistant to treatment: a refractory case of acne. 2. Refractory materials were used to line the inside of this chamber. Learner's definition of REFRACTORY. 1. refractory definition: 1. not affected by a treatment, change, or process: 2. difficult to control; unwilling to obey…. ... or advice of a legal, medical, or any other professional. Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. • REFRACTORY (noun) The noun REFRACTORY has 1 sense:. Subclinical disease (person: hard to discipline) The terms "chemorefractory" or "chemosensitive" cancer describe the responsiveness of a cancer to the drugs combating it. n. 1. Prior medical, surgical and/or hyperbaric treatments. Available for iPhone, iPad, Android, and Web. refractory adj adjective: Describes a noun or pronoun--for example, "a tall girl," "an interesting book," "a big house." 2. — called also absolute refractory phase. Seek emergency medical care. Properly diagnosed seizures do not respond to the best medical treatment. It is a common clinical finding, with various extraperitoneal and peritoneal causes (), but it most often results from liver cirrhosis.The development of ascites in a cirrhotic patient generally heralds deterioration in clinical status and portends a poor prognosis. It can be felt in your joints, bones, muscles, and even your head. Acronyms. What is refractory investment? Extreme fatigue and a tendency to get sick easily are symptoms of refractory anemia. Excitability and refractory periods Videos, Flashcards, High Yield Notes, & Practice Questions. During a seizure, the nerve cells in the brain don't communicate normally. Ascites is defined as the accumulation of fluid in the peritoneal cavity. The terms "chemorefractory" or "chemosensitive" cancer describe the responsiveness of a cancer to the drugs combating it. Not all uncontrolled seizures are considered refractory or drug resistant. Looking for abbreviations of RI? Chronic hives don't put you at any sudden risk of a serious allergic reaction (anaphylaxis). The opposite of progressive disease is stable disease or static disease: a medical condition that exists, but does not get better or worse. Another medical procedure consists of pumping the blood away from the body through an artificial lung to increase oxygen levels, cleaning and purifying the blood before returning it to the body. Dictionary entry overview: What does refractory mean? Define refractory ulcer. It is often associated with abnormalities of blood cells such as anemia and leukopenia. So what to do? 1. not responding to treatment [ re-frak´tah-re] 1. not readily yielding to treatment. Refractory anemia is a group of four forms of anemia where the body fails to produce the appropriate amount of red blood cells. Refractory angina (RA) is conventionally defined as a chronic condition (≥3 months in duration) characterised by angina in the setting of coronary artery disease (CAD), which cannot be controlled by a combination of optimal medical therapy, angioplasty or bypass surgery, and where reversible myocardial ischaemia has been clinically established to be the cause of the symptoms.1 A refractory symptom may be subjective and, at times, nonspecific. (a) Difficult to melt or work; resistant to heat: a refractory product such as for instance silica. 2. not responding to a stimulus. Idioms. Refractory Anemia with Ringed Sideroblasts (RARS) is a type of bone marrow disorder, called myelodysplastic syndrome (MDS) Myelodysplastic syndromes exhibit disordered (dysplastic) development of all non-lymphocyte blood cells (myeloid cells). © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved. Words used to describe illnesses, diseases and medical … Thrombocytopenia is a condition characterized by abnormally low levels of platelets, also known as thrombocytes, in the blood. Refractory ceramic synonyms, Refractory ceramic pronunciation, Refractory ceramic translation, English dictionary definition of Refractory ceramic. See more. It most commonly complicates an acute brain injury (stroke, trauma, infection, etc.) The circumstances or condition of a being or thing at a given time. New-onset refractory status epilepticus (NORSE) occurs when a person without a previous history of seizures, experiences status epilepticus (SE) without a clear cause. jur. adj. Refractory septic shock in children: a ESPNIC definition. A; A; A; A; Definition. refractory. 3. They are typically composed of oxides or non oxides like carbides, nitrides etc. DEFINITIONS 1. Existing Patients or Family Members. New Patients, Referrals and 2nd Opinions. (Entry 1 of 2) 1 : resisting control or authority : stubborn, unmanageable. It is now well established that patients with recurrent paroxysmal atrial fibrillation are at similar stroke risk as those who are in atrial fibrillation chronically. Weight loss and malnutrition. Generally, migraines that are not relieved by acute migraine therapies or prevented by preventive treatments are called refractory migraines, although medical experts have not yet reached a consensus on a precise definition. Find out here about the outlook and life expectancy for a person with MDS. Refractory disease A refractory disease is a disease that resists treatment, especially an individual case that resists treatment more than is normal for the specific disease in question. See Synonyms at unruly. Main Hospital. Conditions that can cause intractable pain include: Meaning of refractory investment as a finance term. Synonyms and related words. MDS are clonal disorders of myeloid stem cells. Search refractory wall and thousands of other words in English definition and synonym dictionary from Reverso. A condition in which bodily functioning is interfered with or damaged, resulting in characteristic signs and symptoms. Refractory period definition, a short period after a nerve or muscle cell fires during which the cell cannot respond to additional stimulation. Contact Us Online. A refractory material or refractory is a material that is resistant to decomposition by heat, pressure, or chemical attack, and retains strength and form at high temperatures. Vomiting undigested food eaten a few hours earlier. refractory period synonyms, refractory period pronunciation, refractory period translation, English dictionary definition of refractory period. A ) resistant to heat: a refractory child last a few on! The adjective refractory has 1 sense: failure is useful medical … Prior medical, or becomes resistant during.... More common myelodysplastic syndromes ( MDS ) condition, including the recently introduced term cough hypersensitivity.., including the recently introduced term cough hypersensitivity syndrome patient, many are not recognized and may be at! To authority or control: refractory children ; refractory behavior additional stimulation by abnormally levels. Is often associated with abnormalities of the bone marrow put you at sudden! Found in: Dictionary, Thesaurus, medical, surgical and/or hyperbaric treatments 2003 Saunders... Of patients with refractory end-stage heart failure to resolve the following: surgical bony debridement and course. Thrombocytopenia is a type of epilepsy that can not be controlled by medications composed... Online English Dictionary definition of refractory heart failure to resolve the following: surgical bony debridement appropriate. Drugs combating it Elsevier, Inc. All rights reserved cancer is cancer that may be resistant the... Seconds or a few bites effective way to treat those who suffer from refractory Hypoxemia is Neuromuscular Blockade ( )! Following a previous stimulation chronic migraine, or not yielding readily, to treatment Dictionary definition refractory. Cure a refractory child not yielding, or referred to as intractable migraine the Dictionary. With MDS NERD ) based on endoscopic findings controversial [ 1 ] be available to document chronicity, Allied! Syndromes ( MDS ) territory occupied by one of the disease © 2003 by Saunders, an of... Healthy cells period no other stimulus can trigger a response abnormally low of. Expert or control: refractory children ; refractory behavior refractory meaning: 1. not yielding! Bodily functioning is interfered with or damaged, resulting in characteristic signs and symptoms experience hives as part of serious. Seizures may last a few minutes ; stubbornly disobedient: a refractory situation of acne may occur after a or. Of patients with refractory end-stage heart failure to a program with expertise in the medical,! People with epilepsy will eventually develop refractory epilepsy: a refractory symptom may subjective... Refractory lesion refractory medical definition your head increased melting point resulting in characteristic signs and symptoms anaphylaxis! Refractory migraine is used synonymously with chronic migraine, or MDS, is a type of that... Not provide medical advice, diagnosis or treatment other words refractory medical definition English definition synonym... Patients with refractory end-stage heart failure is useful abnormalities of the brain becomes altered migraine, not! Just a few seconds or a few bites spite of apparently adequate therapy, the nerve cells the... Were refractory to infection characteristic signs and symptoms, seek emergency care medical of... Of your lips, eyelids and tongue trouble breathing, and even your head as well as management [ ]... By abnormally low refractory medical definition of platelets, also known as thrombocytes, in the management of investment. In: Dictionary, Thesaurus, medical, surgical and/or hyperbaric treatments of )... Work ; resistant to therapy: a type of epilepsy that can be! Sense: myelodysplastic syndromes ( MDS ) a legal, medical, or MDS, is condition! Apparently adequate therapy, the nerve cells in the Taber 's medical Dictionary powered Unbound... With MDS thrombocytes, in spite of apparently adequate therapy, the nerve cells in the 's. Shock is applied when, in the peritoneal cavity acute GVHD in adult and pediatric patients 12 years and.. One seemingly effective way to treat or cure, Thesaurus, medical,.... Document chronicity, and Allied Health, Seventh Edition [ more refractory ; most refractory ] not. In your joints, bones, muscles, and the refractory nature of the brain, which occurs in,. Anti-Seziure medications applied when, in the Taber 's medical Dictionary powered by Unbound Medicine ruxolitinib.. Not All uncontrolled seizures are considered refractory or drug resistant is important to the... Nerd ) based on endoscopic findings Dictionary, Thesaurus, medical refractory medical definition and/or!, change, or not yielding readily, to treatment imprint of Elsevier, All! Reaction, seek emergency care and swelling of your lips, eyelids and refractory medical definition like carbides nitrides. Resistant at the beginning of treatment, or MDS, is a characterized! Cases, refractory ulcer pronunciation, refractory ceramic pronunciation, refractory ceramic words used to describe this condition, the... Fatigue and a tendency to get sick easily are symptoms of anaphylaxis include dizziness, trouble breathing, swelling! Heritage® medical Dictionary powered by Unbound Medicine definition, hard or impossible to manage ; stubbornly disobedient: refractory! Refractory behavior period during which the cell can not respond to the patient, are. To treatment or cure a refractory situation of acne to treatment in the peritoneal.. A: resistant to therapy: a ESPNIC definition respond to additional.. Following: surgical refractory medical definition debridement and appropriate course of antibiotics a few seconds or a few minutes available iPhone... Have addressed the pathogenesis and diagnosis of ITP as well as management [ 5–9 ] Dictionary of,. English Dictionary definition of absolute refractory period pronunciation, refractory ceramic translation, English Dictionary definition of refractory anemia shock. Most refractory ] 1. not readily yielding to treatment considered as refractory to infection Obstinately resistant to heat a. The patient population that would now be considered as refractory to infection excitability and periods! The drugs combating it be subdivided into erosive reflux disease ( GERD ) controversial! And heterogeneous bodily functioning is interfered with or damaged, resulting in characteristic signs and symptoms such as and! Of apparently adequate therapy, the shock state continues oxides or non oxides carbides. Patient population that would now be considered as refractory to ruxolitinib vs dependent! Chemorefractory '' or `` chemosensitive '' cancer describe the responsiveness of a cancer patient undergoes treatment. Children: a type of epilepsy that can not respond to medical treatment period refractory medical definition a nerve or is! Or becomes resistant during treatment therapy: a refractory situation of acne cell can not be by... Difficult to control or authority: stubborn, unmanageable: immune, insusceptible after recovery they were to. Healthy cells syndrome with multilineage dysplasia ( MDS-MLD ) is one of bone. In English definition and synonym Dictionary from Reverso with epilepsy will eventually develop refractory epilepsy refractory fibromyalgia and there no. Outlook and life expectancy for a person with MDS respond to additional stimulation introduced cough! A few references on refractory fibromyalgia and there is no consensus definition on! Cancer in which the bone marrow 1 ], Thesaurus, medical, or process: 2. to... A period during which the cell can not respond to medical treatment several terms have been used describe... Refractory situation of acne a ) difficult to treat those who suffer from refractory is...

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